Which ocular side effect would NOT be expected with Amiodarone?

Which ocular side effect would NOT be expected with Amiodarone?

• A. PSC cataract formation
• B. Anterior subcapsular lens deposits
• C. NAION
• D. Whorl keratopathy

Answer: (A)

Amiodarone’s ocular toxicity profile most often includes corneal changes (whorl keratopathy) and lens deposits, with rare involvement of the optic nerve. The corneal whorl pattern results from deposition in the corneal epithelium and is dose-related, usually harmless but can be seen in routine exams. The lens can develop anterior subcapsular deposits from drug accumulation, which may affect vision if they progress. Optic neuropathy, including NAION, is a recognized though less common serious complication. Posterior subcapsular cataracts are not typical of amiodarone toxicity; they’re more commonly linked to other factors like steroids or diabetes. So, the finding that would not be expected with amiodarone is posterior subcapsular cataract formation.

Amiodarone’s ocular toxicity profile most often includes corneal changes (whorl keratopathy) and lens deposits, with rare involvement of the optic nerve. The corneal whorl pattern results from deposition in the corneal epithelium and is dose-related, usually harmless but can be seen in routine exams. The lens can develop anterior subcapsular deposits from drug accumulation, which may affect vision if they progress. Optic neuropathy, including NAION, is a recognized though less common serious complication. Posterior subcapsular cataracts are not typical of amiodarone toxicity; they’re more commonly linked to other factors like steroids or diabetes. So, the finding that would not be expected with amiodarone is posterior subcapsular cataract formation.