Which drug is an ARB?

Which drug is an ARB?

• A. Lisinopril
• B. Enalapril
• C. Losartan
• D. Hydrochlorothiazide

Answer: (C)

Angiotensin II receptor blockers prevent angiotensin II from binding to the AT1 receptor, so they stop the vasoconstrictor and aldosterone-promoting effects that raise blood pressure. Losartan is an ARB, so it uses this exact mechanism to lower BP. The other drugs work differently: lisinopril and enalapril are ACE inhibitors, which cut down the production of angiotensin II rather than blocking its receptor, and can cause a cough from bradykinin buildup. Hydrochlorothiazide is a diuretic that lowers blood pressure by increasing urine output, not by interfering with the angiotensin system. So Losartan is the drug that is an ARB.

Angiotensin II receptor blockers prevent angiotensin II from binding to the AT1 receptor, so they stop the vasoconstrictor and aldosterone-promoting effects that raise blood pressure. Losartan is an ARB, so it uses this exact mechanism to lower BP. The other drugs work differently: lisinopril and enalapril are ACE inhibitors, which cut down the production of angiotensin II rather than blocking its receptor, and can cause a cough from bradykinin buildup. Hydrochlorothiazide is a diuretic that lowers blood pressure by increasing urine output, not by interfering with the angiotensin system. So Losartan is the drug that is an ARB.