The most common side effect of Metformin is?

The most common side effect of Metformin is?

• A. Diarrhea
• B. Hypoglycemia
• C. Nausea
• D. Vomiting

Answer: (A)

Metformin commonly causes GI upset, with diarrhea being the most frequent side effect, especially when starting treatment or using higher doses. Taking the medication with meals and gradually increasing the dose, or using an extended-release formulation, helps reduce this irritation. Hypoglycemia is not typical with metformin alone because it doesn’t increase insulin release; the risk is mainly when combined with other glucose-lowering drugs. Nausea and vomiting can occur too, but they tend to be less common than diarrhea and often improve as the body adjusts or with dose adjustments.

Metformin commonly causes GI upset, with diarrhea being the most frequent side effect, especially when starting treatment or using higher doses. Taking the medication with meals and gradually increasing the dose, or using an extended-release formulation, helps reduce this irritation. Hypoglycemia is not typical with metformin alone because it doesn’t increase insulin release; the risk is mainly when combined with other glucose-lowering drugs. Nausea and vomiting can occur too, but they tend to be less common than diarrhea and often improve as the body adjusts or with dose adjustments.