Chronic alcoholism can lead to thiamine deficiency which is also known as vitamin __ deficiency.

Chronic alcoholism can lead to thiamine deficiency which is also known as vitamin __ deficiency.

• A. Vitamin B1
• B. Vitamin B2
• C. Vitamin B3
• D. Vitamin B6

Answer: (A)

Thiamine acts as a key cofactor in energy production from carbohydrates, helping enzymes such as pyruvate dehydrogenase and alpha-ketoglutarate dehydrogenase operate properly. In chronic alcoholism, poor intake, malabsorption, and liver depletion reduce thiamine availability, so tissues with high energy demands—especially the brain and nervous system—suffer energy failure. This pattern of deficiency is vitamin B1 deficiency. Since thiamine is vitamin B1, chronic alcohol use leading to deficiency points to vitamin B1 deficiency as the correct label. Other B vitamins—B2, B3, and B6—have distinct roles and deficiency syndromes, so they don’t describe thiamine deficiency.

Thiamine acts as a key cofactor in energy production from carbohydrates, helping enzymes such as pyruvate dehydrogenase and alpha-ketoglutarate dehydrogenase operate properly. In chronic alcoholism, poor intake, malabsorption, and liver depletion reduce thiamine availability, so tissues with high energy demands—especially the brain and nervous system—suffer energy failure. This pattern of deficiency is vitamin B1 deficiency. Since thiamine is vitamin B1, chronic alcohol use leading to deficiency points to vitamin B1 deficiency as the correct label. Other B vitamins—B2, B3, and B6—have distinct roles and deficiency syndromes, so they don’t describe thiamine deficiency.